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Texas Childrens Hospital's mission is to support excellence in patient care, education and research with a commitment to quality service and cost-effective care to enhance the health and well-being of children locally, nationally and internationally. Texas Children's Hospital Integrated Delivery System is committed to a community of healthy children by providing the finest possible pediatric patient care, education and research.

Brad and Vicki Margus founded the A-T Children's Project when two of their young sons were diagnosed with A-T in 1993. Ataxia-telangiectasia is a genetic disease that attacks in early childhood. It progressively affects coordination, predisposes children to lethal cancers, and severely compromises their immune systems. Children with A-T are usually unable to walk by the age of ten and rarely live beyond their teens. By supporting and coordinating aggressive research, we hope to give them a chance to live and to enjoy life's possibilities.